Can medications cause PH?


Yes, some medications can cause PH. Patients who have taken weight loss medications (also known as appetite-suppressant medications or anorexigens) have a higher risk of PAH. These medications include:

  • Aminorex
  • Fenfluramine (Ponderal, Pondamin)
  • Dexfenfluramine (Redux)
  • Phentermine (Ionamin)
  • Mazindol

Patients who have abused recreational drugs are at higher risk for PH. These drugs include:

  • Cocaine
  • Methamphetamine
  • Amphetamine

Some medications used to treat cancer (also known as chemotherapy) have been reported to cause PH. These medications include:

  • Bleomycin
  • Busulfan
  • Carmustine (BCNU)
  • Interferon-alpha
  • Interleukin-2
  • Lomustine (CCNU)
  • Mitomycin C
  • Nitrosoureas
  • Dasatinib

Many other uncommon medications may sometimes cause PH. These medications include:

  • L-tryptophan