Can PH be cured?

Yes, PH can be cured in some patients.

PH can be cured in some patients by surgery, including:

  • Transplantation of the lungs or both the heart and lungs. Transplantation is often a last treatment option in certain patients with PAH.
  • Surgery to remove blood clots in the pulmonary arteries. This surgery, known as pulmonary thromboendarterectomy, is only helpful in patients with PH due to recurrent or multiple blood clots in the lungs (also known as chronic thromboembolic pulmonary hypertension or CTEPH).

In some patients, PH can be temporary. This means that PH may improve and sometimes disappear completely, all by itself. In these patients, PH is usually due to another disease or illness, such as heart failure or blood clots in the lungs.

However, in many patients, PH is usually a permanent condition. In these patients:

  • PH usually does not improve by itself or disappear;
  • Medical treatment can be very effective, but medications do not usually cure PH;
  • In very rare patients, PH may improve dramatically and may even disappear following treatment with certain PH medications, such as oral calcium channel blockers (CCB) and intravenous epoprostenol (Flolan or Caripul).